The course of lectures of the Fundamentals of Health and Safety provides the general information and concepts on security, kinds of dangers, security system, emergencies, the current condition of the technosphere and technosphere safety, criteria and security settings of the technosphere, basic principles, systems and methods of the protection of human and environment from the main types of dangerous and harmful effects of natural, anthropogenic and technogenic origin; methods and principles of control, monitoring and forecasting the dangerous and negative factors; principles, methods and means of organisation of comfortable living conditions based on the relationship of living conditions to health and productivity, classification of emergencies and economic facilities on the the potential dangers; basics of rescue and other urgent activities in emergency situations; legislative and regulatory basics of management of life safety. The textbook is recommended to students enrolled in higher education institutions and for all concerned the study of basics of life safety.